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GSK / Leukeran
Leukeran
Leukeran can cause suppressed bone marrow function, other cancers, birth defects, and infertility.
Leukeran - used for:
Treating certain cancers. It may also be used to treat other conditions as determined by your doctor.
Leukeran is an alkylating agent. It works by binding to the RNA or DNA of certain cancer cells, which helps to slow down their growth and reproduction.
Do NOT use Leukeran if:
- you are allergic to any ingredient in Leukeran
- you are in the first trimester of pregnancy
How does it work?
Leukeran tablets contain the active ingredient chlorambucil, which is a type of anti-cancer or chemotherapy medicine known as an 'alkylating agent'.
Cancers form when some cells within the body multiply uncontrollably and abnormally. These cells spread, destroying nearby tissues. Chlorambucil works by stopping the cancer cells from multiplying. It does this by binding to and damaging the DNA in the cancer cells. This stops the cells from growing and multiplying.
Unfortunately, chlorambucil can also affect normal, healthy cells, particularly those that multiply quickly, such as blood cells and hair cells. The most important side effect is on the bone marrow where blood cells are made. Chlorambucil can decrease the production of blood cells, leaving people susceptible to infection. Regular blood tests are therefore needed to monitor the levels of blood cells.
Chlorambucil is used to treat lymphomas and leukaemias. It is taken by mouth as tablets.
What is it used for?
- Lymph node cancer (Hodgkin's disease)
- Non-Hodgkin's lymphoma
- A rare type of cancer of the lymphatic system (non-Hodgkins lymphoma) called Waldenstrom's macroglobulinaemia
- Chronic lymphocytic leukaemia
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