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Roche / Rivotril
How does it work?
Clonazepam belongs to a group of medicines called the benzodiazepines. It can be used to regulate the activity of nerves.
The brain and nerves are made up of many nerve cells that communicate with each other through electrical signals. These signals must be carefully regulated for the brain and nerves to function properly.
When abnormally rapid and repetitive electrical signals are released in the brain, it becomes over-stimulated and normal function is disturbed. This results in fits or seizures.
GABA is a chemical that, when released in the brain, acts as a calming agent and keeps the nerve activity in balance. Once the brain absorbs the GABA (uptake), this chemical can no longer act on the nerves. Too little GABA, the brain may become overexcited.
Clonazepam acts on receptors in the brain (GABA receptors) to increase the release of GABA. This increases the calming effects of nerve cells by GABA. By calming nerve cells, clonazepam prevents excessively rapid and repetitive firing of electrical signals. Thereby electrical nerve activity in the brain is stabilised, leading to prevention and treatment of fits and maintenance of normal brain function.
What is it used for?
- Absence seizures (petit mal epilepsy)
- Generalised tonic-clonic seizures (grand mal epilepsy)
- Myoclonic seizures
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