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GSK / Zeffix

Zeffix tablets and oral solution contain the active ingredient lamivudine, which is a type of medicine called a nucleoside analogue. Lamivudine is an antiviral medicine used to treat hepatitis B.

Hepatitis B is a virus that infects the liver and leads to liver damage. Once the virus is inside the liver cells it multiplies. Part of this process involves the virus making copies of its genetic material (DNA). This is achieved by a compound essential to the virus, called viral DNA polymerase. Viral DNA polymerase is a compound known as an enzyme. Lamivudine works by blocking the action of this enzyme. This stops the virus from multiplying.

Lamivudine lowers the amount of hepatitis B virus in the body. This leads to a reduction in liver damage and an improvement in liver function.

What is it used for?

• Chronic hepatitis B