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Daclizumab (da-KLIZ-yoo-mab) belongs to a group of medicines known as immunosuppressive agents. It is used to lower the body's natural immunity in patients who receive kidney transplants.

When a patient receives a kidney transplant, the body's white blood cells will try to get rid of (reject) the transplanted kidney. Daclizumab works by preventing the white blood cells from getting rid of the transplanted kidney. The effect of daclizumab on the white blood cells may also reduce the body's ability to fight infections.

What is the most important information I should know about daclizumab?
Because it may cause serious side effects, daclizumab should only be prescribed by a doctor experienced in immunosuppressive therapy and the management of organ transplant patients. Discuss the risks and benefits of using this medication with your doctor.

There may be an increased risk of infection with the use of daclizumab. Contact your doctor immediately if you develop signs of infection such as fever or chills; sore throat, coughing, congestion or other signs of infection; redness, pain, or swelling of a skin wound; or burning or difficult urination.

Treatment with an immunosuppressant such as daclizumab may increase the risk of developing certain types of cancer (e.g., lymphoma). Talk to your doctor about the risks and benefits of using this medication.

What is daclizumab?

  • Daclizumab is an immunosuppressant. Immunosuppressants decrease the actions of the body's immune system.
  • Daclizumab is used to prevent the body from rejecting a transplanted kidney. Daclizumab is usually used as part of a treatment regimen including other medications.
  • Daclizumab may also be used for purposes other than those listed in this medication guide.
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